Advanced Search

Submit Online

Volume 17, Issue 5, May 2025

Articles

FOXO1 enhances G6PD expression to promote cancer cell antioxidative capacity 
Xianhong Zhang, Jie Zhang, Mengmeng Wei, Min Zhao, Xiaoxiong Wang, Yongfeng Hui, Dongdong Yuan, Zijiao Wang, Wei Wu, Peng Jiang, Yujiong Wang, Le Li
J Mol Cell Biol, Volume 17, Issue 5, May 2025, mjaf021, https://doi.org/10.1093/jmcb/mjaf021
Abstract | Full Text 
Intraflagellar transport-associated CCDC92 is required for spermiogenesis and male fertility in mice
Yue Lu, Xirui Zi, Qian Lyu, Qingchao Li, Hanxiao Yin, Yinghao Wang, Qijun Chen, Bingkun Kang, Shanshan Nai, Jun Zhou, Huijie Zhao, Ting Song
J Mol Cell Biol, Volume 17, Issue 5, May 2025, mjaf022, https://doi.org/10.1093/jmcb/mjaf022
Abstract | Full Text 
Aurora B maintains spherical shape of mitotic cells via simultaneously stabilizing myosin II and vimentin 
Chenxi Hou, Fazhi Yu, Cheng Cao, Tianchen Wang, Zihang Pan, Mingru Zhong, Xing Liu, Xuebiao Yao, Kaiguang Zhang, Zhenye Yang, Jing Guo
J Mol Cell Biol, Volume 17, Issue 5, May 2025, mjaf023, https://doi.org/10.1093/jmcb/mjaf023
Abstract | Full Text 

Letter to the Editor

Dimerization of ACAP4 is essential for its function in cell migration 
Hongfei Ma, Jingjing He, Zhiyou Fang, Fangyuan Xiong, Xuannv Zhao, Dongmei Wang, Xiaoyu Song, Chuanhai Fu, Tetsuro Urushidani, Xuebiao Yao, Hongwu Qian, Xing Liu
J Mol Cell Biol, Volume 17, Issue 5, May 2025, mjaf024, https://doi.org/10.1093/jmcb/mjaf024
Abstract | Full Text 

< Previous

Next >

Cover: The image illustrates how the transcription factor FOXO1 promotes cancer cell proliferation and survival under oxidative stress. By upregulating G6PD expression, FOXO1 activates the pentose phosphate pathway, leading to increased NADPH and ribose 5-P production, which bolsters antioxidant defense and nucleotide biosynthesis. The visual highlights the central role of the FOXO1–G6PD axis in metabolic reprogramming and redox homeostasis of cancer cells. See mjaf021 by Zhang et al. for details.