Advanced Search

Submit Online

Volume 17, Issue 2, February 2025

Review

Calciphylaxis: ongoing challenges and treatment opportunities with mesenchymal stem cells
Daoxu Wu, Shijiu Lu, Jiaying Hu, Ming Zeng, Jingjing Wu, Cui Li, Xingfang Tang, Tian Lu, Yi Zhu, Jiayin Liu, Lianju Qin, Ningning Wang
J Mol Cell Biol, Volume 17, Issue 2, February 2025, mjaf009, https://doi.org/10.1093/jmcb/mjaf009
Abstract | Full Text 

Articles

METTL3 modulates colonic epithelium integrity via maintaining the self-renewal and differentiation of Lgr5+ stem cell
Chenbo Ding, Xinhui Yang, Hua Liu, Manolis Roulis, Huifang Chen, Yunzhu Chen, Hao Xu, Yimeng Gao, Jie Zhong, Hua-Bing Li, Youqiong Ye, Wei Cai, Weiguo Hu, Zhengting Wang
J Mol Cell Biol, Volume 17, Issue 2, February 2025, mjae060, https://doi.org/10.1093/jmcb/mjae060
Abstract | Full Text 
Wnt/β-catenin pathway induces cardiac dysfunction via AKAP6-mediated RyR2 phosphorylation and sarcoplasmic reticulum calcium leakage
Ang Li, Yuanyuan Shen, Zhenyan Li, Lin Li
J Mol Cell Biol, Volume 17, Issue 2, February 2025, mjaf002, https://doi.org/10.1093/jmcb/mjaf002
Abstract | Full Text 

Letter to the Editor

Phosphorylation of CENP-C by PLK1 ensures accurate chromosome congression during mitosis
Shanshan He, Cunyu Wang, Hengyi Shao, Chengcheng Hu, Ranran Hu, Ran Liu, Changlu Tao, Chao Wang, Chuanhai Fu, Xing Liu, Xuebiao Yao, Liangyu Zhang
J Mol Cell Biol, Volume 17, Issue 2, February 2025, mjae062, https://doi.org/10.1093/jmcb/mjae062
Abstract | Full Text 

Research Advance

Comments on ‘Vimentin intermediate filaments coordinate actin stress fibers and podosomes to determine the extracellular matrix degradation by macrophages’
Sandrine Etienne-Manneville
J Mol Cell Biol, Volume 17, Issue 2, February 2025, mjaf004, https://doi.org/10.1093/jmcb/mjaf004
Abstract | Full Text 

< Previous

Next >

Cover: Activation of the canonical Wnt signaling pathway upregulates the expression level of its transcriptional target AKAP6, which promotes PKA-mediated phosphorylation of RyR2 and thus induces sarcoplasmic reticulum calcium dysregulation in cardiomyocytes, ultimately leading to cardiac dysfunction with characteristic pathological remodeling, such as hypertrophy and fibrosis. See mjaf002 by Li et al. for details.