cGAS‒STING signaling and function in metabolism and kidney diseases
Juli Bai1,2,* , Feng Liu1,2,*
1Department of Pharmacology, University of Texas Health at San Antonio, San Antonio, TX 78229, USA 2National Clinical Research Center for Metabolic Diseases, Metabolic Syndrome Research Center, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital of Central South University, Changsha 410011, China *Correspondence to:Juli Bai , Email:baij@uthscsa.edu Feng Liu , Email:Liuf001@csu.edu.cn
The cyclic GMP‒AMP synthase (cGAS)‒stimulator of interferon genes (STING) signaling pathway senses the presence of cytosolic DNA and, in turn, triggers downstream signaling to