Volume 17, Issue 7, July 2025

Review

Regulated cell death in organ transplantation: recent developments and mechanistic overview
Qian Chen, Jiashi Sun, Shifan Zhu, Minghui Wu, Hakjun Lee, Azeem Alam, Moradi Kimia, Enqiang Chang, Hailin Zhao, Yue Jin, Daqing Ma
J Mol Cell Biol, Volume 17, Issue 7, July 2025, mjaf034, https://doi.org/10.1093/jmcb/mjaf034
Abstract | Full Text 

Articles

African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation
Jie Fan, Jifei Yang, Zhancheng Tian, Xiaoqiang Zhang, Shuxian Geng, Jianxun Luo, Istvan Boldogh, Qiaoying Zeng, Hong Yin, Guiquan Guan, Qingli Niu
J Mol Cell Biol, Volume 17, Issue 7, July 2025, mjaf029, https://doi.org/10.1093/jmcb/mjaf029
Abstract | Full Text 
AMPK maintains the activation of hepatic stellate cells through mitophagy-induced metabolic reprogramming
Hanmin Wang, Guanzhen Wang, Tao Yin, Hao Li, Hanlin Wang, Yikai Shao, Yuanyuan Li, Rong Hua, Jia Li, Yi Zang
J Mol Cell Biol, Volume 17, Issue 7, July 2025, mjaf030, https://doi.org/10.1093/jmcb/mjaf030
Abstract | Full Text 
Automating classification of treatment responses to combined targeted therapy and immunotherapy in HCC
Bing Quan, Mingrong Dai, Peiling Zhang, Shiping Chen, Jialiang Cai, Yujie Shao, Pengju Xu, Peizhao Li, Lei Yu
J Mol Cell Biol, Volume 17, Issue 7, July 2025, mjaf031, https://doi.org/10.1093/jmcb/mjaf031
Abstract | Full Text 

Research Advance

Cover: Upon encountering Gram-negative bacteria, macrophages initiate the formation of dendrite-like pseudopods (DLPs)
with blunt, bean sprout-like tips through lipopolysaccharide (LPS)-activated TLR4–ARHGEF3–RhoA signaling and cytoskeletal
assembly. The cyclic turnover of linearized actin and pronounced accumulation of vimentin are essential for building and
stabilizing DLPs to enhance the internalization of bacteria by macrophages. See mjaf020 by Fan and Jiu for details.