To cope with various stress conditions, cells turn off house-keeping processes and turn on stress-protective pathways (Rabouille and Alberti, 2017). A successful strategy would also require cells to efficiently reactivate the essential cellular processes once the stress is over. In addition to activation of signaling events, recent studies have shown that formation of certain membraneless assemblies plays a role in stress adaptation (Rabouille and Alberti, 2017). One prominent type of these assemblies is stress granules (SGs), which are composed of translation-arrested messenger RNAs (mRNAs) and many RNA-binding proteins. The assembly of SGs and other ribonucleoprotein granules is driven by numerous interactions of RNA‒protein, protein‒protein, and RNA‒RNA molecules (Protter and Parker, 2016). Liquid‒liquid phase separation is now considered a key mechanism underlying the dynamic and reversible features of these assemblies, which may facilitate the rapid recovery of the molecular activities after stress (Franzmann et al., 2018).