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Volume 15, Issue 1, January 2023

Perspective

Differences in the immunogenicity of engineered circular RNAs
Justin Tai, Y. Grace Chen
J Mol Cell Biol, Volume 15, Issue 1, January 2023, mjad002, https://doi.org/10.1093/jmcb/mjad002
Abstract | Full Text 
CircRNP complexes: from nature to design
Stephen Sukumar Nuthalapati, Corinna Jessica Ulshöfer, Albrecht Bindereif
J Mol Cell Biol, Volume 15, Issue 1, January 2023, mjad006, https://doi.org/10.1093/jmcb/mjad006
Abstract | Full Text 

Articles

RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma 
Silke Lambing, Yu Pan Tan, Paraskevi Vasileiadou, Stefan Holdenrieder, Patrick Müller, Christian Hagen, Stephan Garbe, Rayk Behrendt, Martin Schlee, Jasper G. van den Boorn, Eva Bartok, Marcel Renn, Gunther Hartmann
J Mol Cell Biol, Volume 15, Issue 1, January 2023, mjad001, https://doi.org/10.1093/jmcb/mjad001
Abstract | Full Text 
scHi-CSim: a flexible simulator that generates high-fidelity single-cell Hi-C data for benchmarking 
Shichen Fan, Dachang Dang, Yusen Ye, Shao-Wu Zhang, Lin Gao, Shihua Zhang
J Mol Cell Biol, Volume 15, Issue 1, January 2023, mjad003, https://doi.org/10.1093/jmcb/mjad003
Abstract | Full Text 
Impairment of autophagy promotes human conjunctival fibrosis and pterygium occurrence via enhancing the SQSTM1–NF-κB signaling pathway
Qin He, Yiting Cai, Jiani Huang, Xiaoying He, Wei Han, Wei Chen
J Mol Cell Biol, Volume 15, Issue 1, January 2023, mjad009, https://doi.org/10.1093/jmcb/mjad009
Abstract | Full Text 

Letters to the Editor

Microtubules composed of α4A undergo curved growth mainly mediated by its core structure
Lei Diao, Mingyi Liu, Yanling Liu, Xu Zhang, Lan Bao
J Mol Cell Biol, Volume 15, Issue 1, January 2023, mjad004, https://doi.org/10.1093/jmcb/mjad004
Abstract | Full Text 
Caenorhabditis elegans NMAD-1 functions as a demethylase for actin
Yu Shi, Hui Yang, Jianping Ding
J Mol Cell Biol, Volume 15, Issue 1, January 2023, mjad008, https://doi.org/10.1093/jmcb/mjad008
Abstract | Full Text 

Research Advance

Glutamine synthetase: a tumor suppressor in hepatocellular carcinoma? 
Weiwei Dai, Wei-Xing Zong
J Mol Cell Biol, Volume 15, Issue 1, January 2023, mjad007, https://doi.org/10.1093/jmcb/mjad007
Abstract | Full Text 

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Cover: Engineered circular RNAs (circRNAs) have exciting potential to be novel therapeutics. A clear understanding of the circRNAs’ immunogenicity would provide a foundation for translating circRNAs into therapies as well as offer insight into fundamental principles of how cells differentiate between self and non-self RNAs. Different features on the circRNA could drive immune activation or evasion, and the contribution of some characteristics still remains to be tested. See mjad002 by Tai and Chen for details.