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Volume 10, Issue 3, June 2018

Letter to the Editor

Staurosporine targets the Hippo pathway to inhibit cell growth Free
Xueyan Ma , Peixue Li, Peihao Chen,Jinhui Li, Hongling Huang, Chao Wang,Wenjing Li, Jianping Ding, Yun Zhao ,Fa-Xing Yu, Xiangbing Qi ,and Lei Zhang
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 267-269, https://doi.org/10.1093/jmcb/mjy016
Abstract | Full Text 

Editorial

JMCB in the 10th year: call for changes Free
Jiarui Wu
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 179-179, https://doi.org/10.1093/jmcb/mjy034
Abstract | Full Text 

Articles

Attractor landscape analysis of the cardiac signaling network reveals mechanism-based therapeutic strategies for heart failure Free
Daebeom Park , Ho-Sung Lee , Jun Hyuk Kang , Seon-Myeong Kim , Jeong-Ryeol Gong ,and Kwang-Hyun Cho
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 180-194, https://doi.org/10.1093/jmcb/mjy019
Abstract | Full Text 
MINAR1 is a Notch2-binding protein that inhibits angiogenesis and breast cancer growth Free
Rachel Xi-Yeen Ho , Rosana D. Meyer , Kevin B. Chandler , Esma Ersoy , Michael Park , Philip A. Bondzie , Nima Rahimi , Huihong Xu , Catherine E. Costello , and Nader Rahimi
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 195-204, https://doi.org/10.1093/jmcb/mjy002
Abstract | Full Text 
SKP2 attenuates NF-κB signaling by mediating IKKβ degradation through autophagy Free
Kunpeng Liu , Lei Zhang, Qiang Zhao , Zhiyao Zhao, Feng Zhi, Yunfei Qin ,and Jun Cui
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 205-215, https://doi.org/10.1093/jmcb/mjy012
Abstract | Full Text 
TGFβ signaling hyperactivation-induced tumorigenicity during the derivation of neural progenitors from mouse ESCs Free
Xianfa Yang , Ran Wang, Xiongjun Wang , Guoqing Cai , Yun Qian , Su Feng , Fangzhi Tan ,Kun Chen , Ke Tang , Xingxu Huang , Naihe Jing , and Yunbo Qiao
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 216-228, https://doi.org/10.1093/jmcb/mjy013
Abstract | Full Text 
Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibition Free
Christopher N. J. Young , Natalia Chira , Justyna Ro´g, Rasha Al-Khalidi , Magalie Benard ,Ludovic Galas , Philippe Chan , David Vaudry , Krzysztof Zabłocki , and Dariusz C. Go´ recki
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 229-242, https://doi.org/10.1093/jmcb/mjx030
Abstract | Full Text 
The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened Free
Zizhang Zhou , Xia Yao, Shu Pang , Ping Chen, Weirong Jiang , Zhaoliang Shan ,and Qing Zhang
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 243-257, https://doi.org/10.1093/jmcb/mjx036
Abstract | Full Text 
Senp2 regulates adipose lipid storage by de-SUMOylation of Setdb1 Free
Quan Zheng , Ying Cao, Yalan Chen , Jiqiu Wang , Qiuju Fan , Xian Huang , Yiping Wang, Tianshi Wang , Xiuzhi Wang, Jiao Ma, and Jinke Cheng
J Mol Cell Biol, Volume 10, Issue 3, June 2018, 258-266, https://doi.org/10.1093/jmcb/mjx055
Abstract | Full Text 

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Cover: System-level analysis of the cardiac signaling network suggests mechanism-based therapeutic strategies for heart failure. The reconstructed cardiac signaling network consists of 141 nodes and 274 links; 212 links are activation links (red pointed arrows) and 62 links are inhibition links (blue blunted arrows). Of the 141 nodes, there are 17 input nodes and 15 output nodes. Nodes that are involved in two or more signaling pathways according to the KEGG classification are highlighted with multiple colors that represent the corresponding pathways. See pages 180–194 by Park et al. for details.