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Featured Articles

AMPK maintains the activation of hepatic stellate cells through mitophagy-induced metabolic reprogramming
Regulated cell death in organ transplantation: recent developments and mechanistic overview
Identification and characterization of a TGF-β-independent SMAD4–NFATc1–STAT3 regulatory axis 
Targeting the ubiquitin–proteasome system and drug therapy in colorectal cancer 
Intraflagellar transport-associated CCDC92 is required for spermiogenesis and male fertility in mice
FOXO1 enhances G6PD expression to promote cancer cell antioxidative capacity 
The disruption of COPII vesicles activates HSF-1 through SEC-23
Argon improves microglia-mediated hippocampal neuronal hyperexcitability to alleviate anxiety-like behaviors in mice 
Silencing GGH induces autophagy by increasing folate stress and production of NADH
Combination therapy dramatically promotes remyelination 
Wnt/β-catenin pathway induces cardiac dysfunction via AKAP6-mediated RyR2 phosphorylation and sarcoplasmic reticulum calcium leakage
METTL3 modulates colonic epithelium integrity via maintaining the self-renewal and differentiation of Lgr5+ stem cell
ENO1–BACE2-mediated LDLR cleavage promotes liver cancer progression by remodelling cholesterol metabolism
Novel roles of ammonia in physiology and cancer 
GPI transamidase complex is required for primordial germ cell migration and development in zebrafish

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